Te Whakahononga led a new approach to scientific research aiming to ensure equitable status for mātauranga Māori alongside western knowledge, and mana whenua with researchers and scientists in the search for solutions to kauri dieback and myrtle rust. By seeking to honour the knowledge and traditions of mana whenua and the Te Tiriti o Waitangi the framework provided a foundation to build enduring relationships and trust between mana whenua and Western scientists. In doing so, Te Whakahononga provides a mechanism to empower mana whenua to undertake their own research, and reframe the culture of Western scientists to understand the benefits of authentic co-leadership in science design, implementation and delivery.